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Current Issue. Kerry Grens Mar 22, The vaccine was 79 percent effective at blocking symptomatic infections, according to data from a Phase 3 trial in the US, Chile, and Peru. A US safety oversight board says the data might be incomplete. Lisa Winter Mar 16, Patients who received the drug fared better cognitively and functionally than those taking placebo, but still experienced losses in performance.
Asher Jones Mar 9, Mix-and-match shots could simplify vaccine rollout and stimulate more-robust immune responses. Also, two new sections have been added: Quick Overview Guides are designed to help users get the most from the tutorials, and the PDF Library has all of the tutorial content in a single place, readily available for download.
Please note that audio narration has been removed. Modernization Webinar Materials Available : A recording of the February 18 webinar and slides describing the progress of the modernization effort have been added to the ClinicalTrials.
January 25, Webinar on ClinicalTrials. Updated related FAQs to clarify that responsible parties may only submit certifications for delayed submission of results information prior to the date of i.
The standard submission deadline for results information is no later than 1 year after the ACT's primary completion date. How do I indicate this exemption when registering the clinical trial at ClinicalTrials. HHS et al. If so, when? If the results submission deadline has already passed for an ACT affected by the Federal Court decision in Seife et al.
What are the potential consequences of not submitting required results information for ACTs affected by the Federal Court's decision in Seife et al.
June 16, Results Submitted and Results Returned Dates Available in Archive Site: The dates for Results first submitted and Results returned after quality control review were added to the study record archive site. May 28, Modernization Public Meeting Materials Available: Recordings from the April 30, , virtual public meeting, including transcript and slides, have been added to the ClinicalTrials.
For more details and to register, visit the public meeting website. Responses to the ClinicalTrials. COVID is an emerging, rapidly evolving situation.
These responses will be updated as needed. Updates will be provided when they are available. Results First Posted can be used to find studies based on the date summary results were first available on ClinicalTrials. The Results Submitted field can be used to find study records based on whether the study sponsor or investigator has submitted summary results information and if submissions with QC comments are available.
January 15, Information Page for ClinicalTrials. It will continue to be updated as more information becomes available. January 7, ClinicalTrials. For more information on opportunities to engage with us to enrich and modernize ClinicalTrials. Webinar on ClinicalTrials. Register to learn more about the modernization efforts, the RFI, and ways to share your feedback.
As of January 1, , initial results submissions for applicable clinical trials that do not meet quality control criteria will be publicly posted on ClinicalTrials. Also available is the Major Comments List containing the complete list of brief standardized major comments that may be provided to the responsible party by National Library of Medicine staff during the quality control review conducted to identify apparent errors, deficiencies, or inconsistencies in a submitted study record.
New England Journal of Medicine Article on Results Information Submission: This article describes the current requirements, challenges, and opportunities for results information submission, 10 years after the ClinicalTrials. This and other publications by ClinicalTrials. Materials from the webinar are available on the Training Materials page. A recording of the presentation and slides are available.
When are results due for an applicable clinical trial ACT , if a certification of delay for an approved, licensed, or cleared product "certify new use" has been submitted under 42 CFR Skip to main content Thank you for visiting nature.
Jones Nature Reviews Nephrology , Latest Research and Reviews Research 12 January Open Access Tolerogenic nanoparticles mitigate the formation of anti-drug antibodies against pegylated uricase in patients with hyperuricemia Anti-drug antibodies ADA induced by biologic drugs may hamper the efficacy of treatment, so inhibiting ADA induction is desirable.
Nature Communications 13 , Levi Spinal Cord , Reviews 08 January Assessing temporal eating pattern in free living humans through the myCircadianClock app Emily N. Weir Nature Medicine , Research Highlights 04 January Use of platelet-rich plasma for knee OA not supported by RCT results In a rigorous randomized controlled trial, treatment with platelet-rich plasma did not improve knee osteoarthritis symptoms or slow disease progression.
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